pH influenced molecular switching with micelle bound cavitands.

نویسندگان

  • Yeon Joo Kim
  • Mark T Lek
  • Michael P Schramm
چکیده

A series of resorcinarene host-amphiphilic guest complexes have been developed where guest orientation in the host is drastically influenced by pH. Guests appended with a trimethylammonium and a tert-butyl group switch orientation by 180° in response to a buildup of negative charge in the cavitand host.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Structure and stabilizing interactions of casein micelles probed by high-pressure light scattering and FTIR.

Caseins form heterogeneous micelles composed of three types of disordered protein chains (α, β, κ), which include protein-bound calcium phosphate particles. We probe the stability limits of the micelle by applying hydrostatic pressure. The resulting changes of the size distribution and the average molecular weight are recorded in situ with static and dynamic light scattering. Pressure induces i...

متن کامل

In Vitro Cytotoxic Activity and Binding Properties of Curcumin in the Presence of β-Casein Micelle Nanoparticles

Curcumin (CUR) is the active curcuminoid with many physiological, biochemical, and pharmacological properties. Solubility and stability of CUR is the limiting factors for realizing its therapeutic potential. Bovine β-casein is an abundant milk protein that is highly amphiphilic and self-assembles into stable micellar nanoparticles in aqueous solution. β-Casein nanoparticle can solubilize CUR mo...

متن کامل

Evidence for Bound and Free Water Species in the Hydration Shell of an Aqueous Micelle

Our atomistic molecular dynamics simulations reveal the existence of bound and free water molecules in the hydration layer of an aqueous micelle. The bound water molecules can be either singly or doubly hydrogen bonded to the polar head group on the surface of the micelle. The ratio of bound to free water is found to be approximately equal to 9:1 at 300 K. email:[email protected] email:bbagchi@...

متن کامل

Purification and properties of a membrane-associated, folate-binding protein from Lactobacillus casei.

A folate-binding protein has been solubilized from Lactobacillus casei by treatment of membrane preparations with Triton X-100 in the presence of [3H]folate. The protein-folate complex was purified 100-fold and recovered in a 22% yield by adsorption and elution from microgranular silica (Quso G-32), followed by passage through Sephadex G-150. When subjected to sodium dodecyl sulfate/polyacrylam...

متن کامل

Self-assembled capsules based on tetrafunctionalized calix[4]resorcinarene cavitands.

Calix[4]resorcinarene-based cavitands with a bowl-shaped aromatic cavity are widely used as scaffolds for covalently bound and self-assembled capsules. There are two main categories of calix[4]resorcinarene-based cavitands that are tetrafunctionalized at the upper (wider) rim: one category includes derivatives that have functionalized bridges between pairs of hydroxy groups of the calix[4]resor...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 47 34  شماره 

صفحات  -

تاریخ انتشار 2011